反应详情

4.00 g of (±)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole was dissolved in 10 mL of hot methanol and 2.2 mL of 48% hydrobromic acid was added. The obtained suspension was stirred, cooled and precipitated solid was filtered off. The cake was washed with cold methanol and air-dried to give 2.7 g of (±)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole monohydrobromide with m.p. 236-245° C.

1. temperaturecooled
2. customprecipitated solid
3. filtrationwas filtered off
4. washThe cake was washed with cold methanol
5. customair-dried