Sodium Iodide → HCID 22049319, compound

HRID 2088028Notes

Reaction equation

HRID 2088028 reaction equation
C([O-])([O-])=O.[K+].[K+].[Na+].[I-].Cl[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]([C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=1)=[O:17].[CH3:25][CH:26]([CH3:42])[C:27]([NH:29][C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([CH:36]2[CH2:41][CH2:40][NH:39][CH2:38][CH2:37]2)[CH:31]=1)=[O:28]>>[Cl:24][C:21]1[CH:22]=[CH:23][C:18]([C:16](=[O:17])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][N:39]2[CH2:40][CH2:41][CH:36]([C:32]3[CH:31]=[C:30]([NH:29][C:27](=[O:28])[CH:26]([CH3:25])[CH3:42])[CH:35]=[CH:34][CH:33]=3)[CH2:37][CH2:38]2)=[CH:19][CH:20]=1

Participants

5

Reactant 4

HCID 5238Sodium IodideHCID 11430Potassium CarbonateHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 220494667-Chloro-1-(4-chlorophenyl)heptan-1-one

Product 1

HCID 22049319HCID 22049319, compound

Procedure

Prepared by Procedure K and Scheme E using K2CO3 instead of Na2CO3 and NaI instead of KI and 7-chloro-1-(4-chlorophenyl)-1-heptanone and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 469.1 (M+H)+.

Workup

  1. customPrepared by Procedure K and Scheme E

Sources & evidence

ORD record
ord-c57c277c15674321a1f5f07788e22915
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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