Toluene → 4-Chloromethyl-5-(4-trifluoromethylphenyl)isoxazole
Reaction equation
[CH3:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]([CH2:14][OH:15])[cH:11][n:12][o:13]2)[cH:7][cH:8]1)([F:16])[F:17].[O:18]1[CH2:19][CH2:20][CH2:21][CH2:22]1.[S:23]([Cl:24])([Cl:25])=[O:26]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]([CH2:14][Cl:25])[cH:11][n:12][o:13]2)[cH:7][cH:8]1)([F:16])[F:17]Participants
5
Sources & evidence
- ORD record
- ord-a11c2deed740431cbcf7121d490ec970
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…