反应详情

Add 4 M hydrochloric acid in dioxane (28.57 μL, 1.0 eq) to a solution of (R)-4-(4-(4-ethyl-1-(2-(pyrrolidin-1-yl)ethyl)-1H-imidazol-2-yl)piperidin-1-yl)-5-methyl-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-one (50.00 mg, 0.11 mmol) in dichloromethane (1 mL) at room temperature and stir for 15 minutes. Concentrate in vacuo to give the title compound (54.00 mg, 100%). MS (ES) m/z=438 [M]+.

1. concentrationConcentrate in vacuo