Dimethylformamide dimethyl acetal → HCID 66778180, compound

HRID 2090881Notes

Reaction equation

HRID 2090881 reaction equation
[CH3:1][O:2][CH2:3][C:4](=O)[CH2:5][C:6]([O:8][CH3:9])=[O:7].[CH3:11]OC(OC)N(C)C.Cl.[CH3:20][O:21][C:22]1[CH:27]=[CH:26][C:25]([NH:28][NH2:29])=[CH:24][CH:23]=1>>[CH3:1][O:2][CH2:3][C:4]1[C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:11][N:28]([C:25]2[CH:26]=[CH:27][C:22]([O:21][CH3:20])=[CH:23][CH:24]=2)[N:29]=1

Participants

4

Reactant 3

HCID 78373Dimethylformamide dimethyl acetalHCID 123500Methyl 4-methoxyacetoacetateHCID 27239044-Methoxyphenylhydrazine hydrochloride

Product 1

HCID 66778180HCID 66778180, compoundYield 50%

Procedure

Using methyl 4-methoxyacetoacetate (5.8 g), dimethylformamide dimethylacetal (5.4 mL) and 4-methoxyphenylhydrazine hydrochloride (7.0 g) and in the same manner as in Example 15(1), the title object compound (5.5 g, 50%) was obtained as a white solid.

Sources & evidence

ORD record
ord-994fb35e9d66404bba1a2df70f95c034
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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