Phenylhydrazine hydrochloride → HCID 66777473, compound

HRID 2090884Notes

Reaction equation

HRID 2090884 reaction equation
[CH3:1][O:2][CH2:3][C:4](=O)[CH2:5][C:6]([O:8][CH3:9])=[O:7].[CH3:11]OC(OC)N(C)C.Cl.[C:20]1([NH:26][NH2:27])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH3:1][O:2][CH2:3][C:4]1[C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:11][N:26]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[N:27]=1

Participants

4

Reactant 3

HCID 60962Phenylhydrazine hydrochlorideHCID 78373Dimethylformamide dimethyl acetalHCID 123500Methyl 4-methoxyacetoacetate

Product 1

HCID 66777473HCID 66777473, compoundYield 55%

Procedure

Using methyl 4-methoxyacetoacetate (7.9 g), dimethylformamide dimethylacetal (7.2 mL) and phenylhydrazine hydrochloride (5.8 g) and in the same manner as in Example 15(1), the title object compound (7.3 g, 55%) was obtained as a pale-yellow solid.

Sources & evidence

ORD record
ord-c251c6b632df4a2dbd86795abdb6afe0
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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