Methylamine → 4-Chloro-3-(3-{[5-cyano-2-propyl-4-(trifluoromethyl)-1H-indol-1-yl]methyl}-1,2,4-oxadiazol-5-yl)-N-methylbenzamide

HRID 209161Notes

Reaction equation

HRID 209161 reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:35][NH2:36].[Cl:1][c:2]1[c:3](-[c:11]2[n:12][c:13]([CH2:16][n:17]3[c:18]([CH2:32][CH2:33][CH3:34])[cH:19][c:20]4[c:21]([C:28]([F:29])([F:30])[F:31])[c:22]([C:26]#[N:27])[cH:23][cH:24][c:25]34)[n:14][o:15]2)[cH:4][c:5]([C:6](=[O:7])[Cl:8])[cH:9][cH:10]1>>[Cl:1][c:2]1[c:3](-[c:11]2[n:12][c:13]([CH2:16][n:17]3[c:18]([CH2:32][CH2:33][CH3:34])[cH:19][c:20]4[c:21]([C:28]([F:29])([F:30])[F:31])[c:22]([C:26]#[N:27])[cH:23][cH:24][c:25]34)[n:14][o:15]2)[cH:4][c:5]([C:6](=[O:7])[NH:36][CH3:35])[cH:9][cH:10]1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 8028TetrahydrofuranHCID 578000844-Chloro-3-(3-{[5-cyano-2-propyl-4-(trifluoromethyl)-1H-indol-1-yl]methyl}-1,2,4-oxadiazol-5-yl)benzoyl chloride

Product 1

HCID 578002064-Chloro-3-(3-{[5-cyano-2-propyl-4-(trifluoromethyl)-1H-indol-1-yl]methyl}-1,2,4-oxadiazol-5-yl)-N-methylbenzamide

Sources & evidence

ORD record
ord-25e77099c38f4aba9e108a6d0efef75e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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