Tetrahydrofuran → 5-[3-(1,1-dimethylethyl)-1H-pyrazol-1-yl]-3-[3-(trifluoromethyl)phenyl]-4-thiazolidinone

HRID 209193Notes

Reaction equation

HRID 209193 reaction equation
[CH3:30][C:31]([CH3:32])([CH3:33])[c:34]1[n:35][nH:36][cH:37][cH:38]1.[O:1]=[C:2]([O:3][CH2:4][CH3:5])[N:6]=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[O:58]1[CH2:59][CH2:60][CH2:61][CH2:62]1.[OH:13][CH:14]1[C:15](=[O:29])[N:16]([c:19]2[cH:20][c:21]([C:25]([F:26])([F:27])[F:28])[cH:22][cH:23][cH:24]2)[CH2:17][S:18]1.[c:39]1([P:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[cH:53][cH:54][cH:55][cH:56][cH:57]1>>[CH:14]1([n:36]2[n:35][c:34]([C:31]([CH3:30])([CH3:32])[CH3:33])[cH:38][cH:37]2)[C:15](=[O:29])[N:16]([c:19]2[cH:20][c:21]([C:25]([F:26])([F:27])[F:28])[cH:22][cH:23][cH:24]2)[CH2:17][S:18]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 21881985HCID 21881985, compoundHCID 178441177HCID 178441177, compound

Product 1

HCID 218819915-[3-(1,1-dimethylethyl)-1H-pyrazol-1-yl]-3-[3-(trifluoromethyl)phenyl]-4-thiazolidinone

Sources & evidence

ORD record
ord-3206920e5ee64b7387f91ecba679416a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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