Hydrochloric Acid → HCID 59574324, compound

HRID 2092100Notes

Reaction equation

HRID 2092100 reaction equation
Cl.[N:2]1[CH:7]=[CH:6][C:5]([CH2:8][NH:9][NH2:10])=[CH:4][CH:3]=1.[C:11](O)(=[O:18])/[C:12](=[C:14](\[CH:16]=O)/[Br:15])/[Br:13].Cl>C(O)C>[Br:13][C:12]1[C:11](=[O:18])[N:9]([CH2:8][C:5]2[CH:6]=[CH:7][N:2]=[CH:3][CH:4]=2)[N:10]=[CH:16][C:14]=1[Br:15]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3033972Mucobromic AcidHCID 22728080HCID 22728080, compound

Product 1

HCID 59574324HCID 59574324, compoundYield 59%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4-Picolylhydrazine hydrochloride (500 mg, 3.13 mmol), mucobromic acid (807 mg, 3.13 mmol) and concentrated hydrochloric acid (500 μL) in ethanol (5 mL) were stirred at 90° C. for 1 day. After completion of the reaction, the resulting crystals were collected by filtration, washed with methanol and dried to give the desired product (59% yield).

Workup

  1. customAfter completion of the reaction
  2. filtrationthe resulting crystals were collected by filtration
  3. washwashed with methanol
  4. customdried

Sources & evidence

ORD record
ord-b9305bb9f1a64a73a42c22ac451b4985
Source dataset
uspto-grants-2013_05
Patent number
US08440666B2

Reaction notes

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