HCID 59393690, compound → HCID 59393695, compound

HRID 2092131Notes

Reaction equation

HRID 2092131 reaction equation
[C:1]([O:4][CH2:5][C:6]([O:8]/[N:9]=[C:10](/[NH2:36])\[C:11]1[CH:12]=[N:13][C:14]([C:17]([C:22]2[CH:27]=[CH:26][C:25]([C:28]3[CH:29]=[N:30][CH:31]=[C:32]([O:34][CH3:35])[CH:33]=3)=[CH:24][CH:23]=2)([CH3:21])[CH:18]([CH3:20])[CH3:19])=[CH:15][CH:16]=1)=O)(=[O:3])[CH3:2]>C1(C)C(C)=CC=CC=1>[C:1]([O:4][CH2:5][C:6]1[O:8][N:9]=[C:10]([C:11]2[CH:12]=[N:13][C:14]([C:17]([C:22]3[CH:27]=[CH:26][C:25]([C:28]4[CH:29]=[N:30][CH:31]=[C:32]([O:34][CH3:35])[CH:33]=4)=[CH:24][CH:23]=3)([CH3:21])[CH:18]([CH3:19])[CH3:20])=[CH:15][CH:16]=2)[N:36]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 1

HCID 59393690HCID 59393690, compound

Product 1

HCID 59393695HCID 59393695, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A solution of 1b (0.896 mmol) in xylene (6.00 mL) was heated to 110° C. for approximately 1 h. After cooling to rt, the reaction mixture was concentrated in vacuo to afford the title compound 1c, which was used without further purification in the subsequent reaction. m/z (ES) 473 (MH)+.

Workup

  1. concentrationthe reaction mixture was concentrated in vacuo

Sources & evidence

ORD record
ord-f5e9d3a56c9e4af2b3956c16d97a0c98
Source dataset
uspto-grants-2013_05
Patent number
US08440672B2

Reaction notes

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