Hydrogen Bromide → HCID 51038898, compound

HRID 2092649Notes

Reaction equation

HRID 2092649 reaction equation
C(OC(=O)[NH:7][CH2:8][C:9]12[CH2:18][CH:13]3[CH2:14][CH:15]([CH2:17][CH:11]([CH:12]3[O:19][CH3:20])[CH2:10]1)[CH2:16]2)(C)(C)C.Br>CCOCC>[CH3:20][O:19][CH:12]1[CH:13]2[CH2:18][C:9]3([CH2:8][NH2:7])[CH2:16][CH:15]([CH2:17][CH:11]1[CH2:10]3)[CH2:14]2

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 67054470HCID 67054470, compound

Product 1

HCID 51038898HCID 51038898, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To 16A (30 mg, 0.10 mmol) in was added HBr (30% in HOAc) 1 mL and the mixture was stirred at rt for 2 h. Ether (10 mL×2) was added and the resulting precipitate was collected and dried under vacuum to give the title compound as hydrogen bromide salts (16). LC-MS (ESR): m/z=196 [M+H]+.

Workup

  1. customthe resulting precipitate was collected
  2. customdried under vacuum

Sources & evidence

ORD record
ord-7942e5bb4a784194871b156774f1bca2
Source dataset
uspto-grants-2013_05
Patent number
US08440720B2

Reaction notes

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