反应详情

4,4-difluorocyclohexylamine hydrochloride (8) is acylated with 2,2,2-trichloroethyl carbonochloridate (9) using an organic base such as triethylamine in an inert solvent such as dichloromethane to give 2,2,2-trichloroethyl 4,4-difluorocyclohexylcarbamate, (7), Step 1.