HRID2095560

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID73768

1-Isocyanato-4-(trifluoromethyl)benzene

C8H4F3NO

结构：C[C@@H]1NCCN(CCCC(=O)N2CCC3(CC3)[C@H](O)C2)C1=O

HCID67074162

未命名化合物

2 次

PRODUCTS

生成物

结构：C[C@H]1C(=O)N(CCCC(=O)N2CCC3(CC3)[C@H](O)C2)CCN1C(=O)Nc1ccc(C(F)(F)F)cc1

HCID52913245

未命名化合物

收率 32%

PROCEDURE

实验过程

In analogy to the procedure described in Example 25, (S)-1-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-3-methyl-piperazin-2-one (intermediate 13) and 4-(trifluoromethyl)phenyl isocyanate gave the titled compound in 32% yield as white foam. MS: 497.2 (MH+).