反应详情

Using N-[6-(4-amino-3-chlorophenoxy)imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide (160 mg, 0.467 mmol), 1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid (150 mg, 0.607 mmol), N,N-dimethylformamide (2 mL), N,N-diisopropylethylamine (161 μL, 0.934 mmol) and HATU (230.8 mg, 0.607 mmol) and in the same manner as in Example 60, the title compound (250 mg, 94%) was obtained as a white solid.