反应详情

(R)-1-[4-(benzyloxy)-3-nitrophenyl]-2-bromoethanol (0.200 g, 0.569 mmol) in 1:1 THF:toluene (5 mL) was reacted with 1% (w/w) PtO2 on a Parr shaker at 45 psi at it overnight. The next morning the PtO2 was removed by filtration over celite. The product was concentrated to give the title compound. ES/MS calcd. for C15H17BrNO2+ 322.0, found m/z=322 (M+H)+.

1. customThe next morning the PtO2 was removed by filtration over celite
2. concentrationThe product was concentrated