反应详情

A solution of 34B (710 mg, 2.37 mmol) in MeOH (8 mL) was treated with 20% palladium hydroxide on carbon (110 mg). The resulting slurry was stirred under a hydrogen atmosphere for 4 hours, and then filtered through a 0.4 μm polycarbonate membrane to remove the catalyst. The filtrate was concentrated to give 34C as a white solid (636 mg, 99%).

1. filtrationfiltered through a 0.4 μm polycarbonate membrane
2. customto remove the catalyst
3. concentrationThe filtrate was concentrated