Potassium Cation → 2,2,2-Trifluoro-1-[2-(3-trifluoro methyl-pyrazol-1-yl)-phenyl]-ethanol

HRID 209997Notes

Reaction equation

HRID 209997 reaction equation
[CH3:29][NH:30][CH:31]1[CH2:32][CH2:33][CH2:34][CH2:35][CH:36]1[NH:37][CH3:38].[CH3:39][CH2:40][O:41][C:42](=[O:43])[CH3:44].[CH3:47][c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1.[Cu:45][I:46].[F:14][C:15]([c:16]1[n:17][nH:18][cH:19][cH:20]1)([F:21])[F:22].[F:1][C:2]([CH:3]([OH:4])[c:5]1[c:6]([I:11])[cH:7][cH:8][cH:9][cH:10]1)([F:12])[F:13].[K+:23].[K+:24].[O-:25][C:26]([O-:27])=[O:28]>>[F:1][C:2]([CH:3]([OH:4])[c:5]1[c:6](-[n:18]2[n:17][c:16]([C:15]([F:14])([F:21])[F:22])[cH:20][cH:19]2)[cH:7][cH:8][cH:9][cH:10]1)([F:12])[F:13]

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 1140TolueneHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 5510741-N,2-N-dimethylcyclohexane-1,2-diamineHCID 18070343-(Trifluoromethyl)pyrazoleHCID 667436982-Iodo-alpha-(trifluoromethyl)benzyl Alcohol

Product 1

HCID 866210922,2,2-Trifluoro-1-[2-(3-trifluoro methyl-pyrazol-1-yl)-phenyl]-ethanol

Sources & evidence

ORD record
ord-10a93ddc1e974addb3643e05d407ebc5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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