Hydrochloric Acid → HCID 76608782, compound

HRID 2101120Notes

Reaction equation

HRID 2101120 reaction equation
[CH3:1][O:2][C:3]1[C:4]([CH3:13])=[C:5]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[CH2:7][CH2:6]2.C([O:18][N:19]=O)CCC.Cl>CO>[CH3:1][O:2][C:3]1[C:4]([CH3:13])=[C:5]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[C:7](=[N:19][OH:18])[CH2:6]2

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 10996Butyl nitriteHCID 57799680HCID 57799680, compound

Product 1

HCID 76608782HCID 76608782, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 5-Methoxy-4-methyl-indan-1-one (3.1 g) in MeOH at 40° C. was added n-butylnitrite (2.5 mL) followed by concentrated HCl (2.3 ml). The solution was stirred for 30 min during which time a precipitate was formed. The precipitate was collected and dried to yield the crude product as a white solid.

Workup

  1. customwas formed
  2. customThe precipitate was collected
  3. customdried

Sources & evidence

ORD record
ord-ac2e6c5f9a764234a787b786cea4bfed
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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