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HRID2101781

反应详情

EQUATION

反应方程式

HRID 2101781 的结构方程式

REACTANTS

反应物

2
结构：CN(C)C=O.O
HCID21962138

N,N-Dimethylformamide--water (1/1)

C3H9NO2

结构：CC1(C)OC(=O)C(C(c2ccc(O)cc2)C2CC2)C(=O)O1
HCID57672484

未命名化合物

PRODUCTS

生成物

1
结构：O=C(O)CC(c1ccc(O)cc1)C1CC1
HCID57672525

3-Cyclopropyl-3-(4-hydroxyphenyl)propanoic acid

C12H14O3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

A solution of 21.2 in 10:1 DMF/water (48 mL) was stirred overnight at 90° C. The mixture was cooled to room temperature, diluted with EtOAc, washed with 1 N HCl and brine, dried (MgSO4), and concentrated to afford 21.3. The crude product was used without further purification.

WORKUP

后处理

  1. washwashed with 1 N HCl and brine
  2. dry with materialdried (MgSO4)
  3. concentrationconcentrated