Hydrochloric Acid → HCID 57804109, compound

HRID 2102940Notes

Reaction equation

HRID 2102940 reaction equation
C[O:2][C:3](=[O:17])[C:4]1[CH:9]=[CH:8][C:7](/[CH:10]=[CH:11]/[C:12]([CH3:15])([CH3:14])[CH3:13])=[CH:6][C:5]=1[CH3:16].[OH-].[Li+].CO.Cl>O>[CH3:13][C:12]([CH3:15])([CH3:14])/[CH:11]=[CH:10]/[C:7]1[CH:8]=[CH:9][C:4]([C:3]([OH:17])=[O:2])=[C:5]([CH3:16])[CH:6]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 887Methanol2×HCID 3939Lithium HydroxideHCID 68701317HCID 68701317, compound

Product 1

HCID 57804109HCID 57804109, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of (E)-4-(3,3-dimethylbut-1-enyl)-2-methylbenzoic acid methyl ester (6.5 g, 0.028 mol) and lithium hydroxide (3.4 g, 0.14 mol) in a mixture of methanol (50 mL, 1 mol) and water (150 mL) was heated to reflux for 3 hours. Most of the methanol was stripped off and the aqueous solution was carefully acidified with conc. HCl. The white precipitate was filtered, washed with water and vacuum dried. m/z=217.1 (M−1).

Workup

  1. temperaturewas heated
  2. temperatureto reflux for 3 hours
  3. filtrationThe white precipitate was filtered
  4. washwashed with water and vacuum
  5. customdried

Sources & evidence

ORD record
ord-b6d59efd709b49deb0b0c9f6a5b32aab
Source dataset
uspto-grants-2009_08
Patent number
US07576099B2

Reaction notes

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