N-methyl-2-pyrrolidone → 3-(2-chlorophenyl)-7-(tetrahydropyran-4-ylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one
Reaction equation
[CH3:36][N:37]1[CH2:38][CH2:39][CH2:40][C:41]1=[O:42].[Cl:1][c:2]1[c:3]([N:8]2[C:9](=[O:28])[NH:10][c:11]3[n:12][c:13]([S:18]([CH2:19][c:20]4[cH:21][cH:22][cH:23][cH:24][cH:25]4)(=[O:26])=[O:27])[n:14][cH:15][c:16]3[CH2:17]2)[cH:4][cH:5][cH:6][cH:7]1.[NH2:29][CH:30]1[CH2:31][CH2:32][O:33][CH2:34][CH2:35]1>>[Cl:1][c:2]1[c:3]([N:8]2[C:9](=[O:28])[NH:10][c:11]3[n:12][c:13]([NH:29][CH:30]4[CH2:31][CH2:32][O:33][CH2:34][CH2:35]4)[n:14][cH:15][c:16]3[CH2:17]2)[cH:4][cH:5][cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-b00d382b990d4c40b0921349bd2fd26d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…