HRID2104344

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID79341

Piperidin-4-ol

C5H11NO

$结构：C/C(=C\C(=O)O)CC(C)(C)NC(=O)OC(C)(C)C$

HCID10753633

未命名化合物

结构：CN(C(=O)OC(C)(C)C)[C@H](Cc1ccc(-c2ccccc2)cc1)C(=O)O

HCID20694694

未命名化合物

结构：CN(C(=O)OC(C)(C)C)[C@H](Cc1cccs1)C(=O)O

HCID54365014

未命名化合物

PRODUCTS

生成物

$结构：C/C(=C\C(=O)N(C)[C@H](Cc1ccc(-c2ccccc2)cc1)C(=O)N(C)[C@H](Cc1cccs1)C(=O)N1CCC(O)CC1)CC(C)(C)N$

HCID10952382

未命名化合物

PROCEDURE

实验过程

This compound was prepared as in example 1 but using 4-hydroxypiperidine, (2R)-2-(N-tert-butoxycarbonyl-N-methylamino)-3-(2-thienyl)propionic acid and (2R)-2-(N-tert-butoxycarbonyl-N-methylamino)-3-(biphenyl-4-yl)propionic acid and (2E)-5-tert-butoxycarbonylamino-3,5-dimethylhex-2-enoic acid as starting materials.

WORKUP

后处理

customThis compound was prepared as in example 1

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-95389608975b423db43fac8ffd0ef7b7
来源数据集: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07576062B2
来源说明: uspto-grants-2009_08

反应 SMILES

[OH:1][CH:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.C(O[C:13]([N:15]([C@H:17]([CH2:21][C:22]1[S:23][CH:24]=[CH:25][CH:26]=1)[C:18]([OH:20])=O)[CH3:16])=[O:14])(C)(C)C.C(O[C:32]([N:34]([C@H:36]([CH2:40][C:41]1[CH:46]=[CH:45][C:44]([C:47]2[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=2)=[CH:43][CH:42]=1)C(O)=O)[CH3:35])=[O:33])(C)(C)C.C(OC([NH:60][C:61]([CH3:70])([CH3:69])[CH2:62]/[C:63](/[CH3:68])=[CH:64]/C(O)=O)=O)(C)(C)C>>[C:44]1([C:47]2[CH:48]=[CH:49][CH:50]=[CH:51][CH:52]=2)[CH:43]=[CH:42][C:41]([CH2:40][C@@H:36]([N:34]([CH3:35])[C:32](=[O:33])/[CH:64]=[C:63](\[CH3:68])/[CH2:62][C:61]([NH2:60])([CH3:70])[CH3:69])[C:13](=[O:14])[N:15]([C@H:17]([CH2:21][C:22]2[S:23][CH:24]=[CH:25][CH:26]=2)[C:18]([N:5]2[CH2:6][CH2:7][CH:2]([OH:1])[CH2:3][CH2:4]2)=[O:20])[CH3:16])=[CH:46][CH:45]=1