反应详情

To a solution of 1-(3-bromophenyl)propan-1-one (2.00 g, 9.39 mmol) in 10 mL TFA, was added triethylsilane (4.50 mL, 28.2 mmol). The mixture was stirred at rt for 20 h, then concentrated. The crude material was purified by flash chromatography to afford 350 mg of Intermediate 214.1 as a colorless oil.

1. concentrationconcentrated
2. customThe crude material was purified by flash chromatography