Iodoethane → HCID 11492795, compound

HRID 2105943Notes

Reaction equation

HRID 2105943 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:9]1[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1.C(=O)([O-])[O-:16].[K+].[K+].I[CH2:22][CH3:23]>C(#N)C>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1([OH:16])[CH2:14][CH2:13][N:12]([CH2:22][CH3:23])[CH2:11][CH2:10]1

Participants

5

Reactant 3

HCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 17895683HCID 17895683, compound

Product 1

HCID 11492795HCID 11492795, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Preparation according to Example 2: 4-(2,3-dichlorophenyl)piperidine (0.02 g, 0.081 mmol), acetonitrile (2 ml), potassium carbonate (0.02 g, 0.14 mmol), iodoethane (0.007 ml, 0.082 mmol). MS m/z (relative intensity, 70 eV) 275 (M+, 14), 274 (M+, bp), 260 (67), 258 (bp), 240 (23), 173 (9).

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-9abc3c609eeb468d993c1c38ac5d7f80
Source dataset
uspto-grants-2009_08
Patent number
US07579474B2

Reaction notes

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