Ammonium Hydroxide → 110608-00-9

HRID 2106605Notes

Reaction equation

HRID 2106605 reaction equation
[C:1]([CH:4]([O:6][C:7]1[N:11]=[CH:10][N:9]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([Cl:18])[CH:13]=2)[N:8]=1)[CH3:5])(O)=[O:2].C(N1C=CN=C1)([N:21]1C=CN=C1)=O.[OH-].[NH4+]>>[Cl:18][C:14]1[CH:13]=[C:12]([N:9]2[CH:10]=[N:11][C:7]([O:6][CH:4]([C:1]([NH2:21])=[O:2])[CH3:5])=[N:8]2)[CH:17]=[CH:16][CH:15]=1

Participants

4

Reactant 3

HCID 14923Ammonium HydroxideHCID 682631,1'-CarbonyldiimidazoleHCID 15016263HCID 15016263, compound

Product 1

HCID 163822110608-00-9Yield 46.6%

Procedure

The process was carried out as was Example 45, starting with 2.8 g of the compound of Example 25, 2.5 g of carbonyldiimidazole and 4 ml of ammonium hydroxide. The product was recrystallized from toluene and then from ethanol to obtain 1.3 g of the desired product, m.p. 143°-145°.

Workup

  1. customThe product was recrystallized from toluene

Sources & evidence

ORD record
ord-0a39f24400864dc18b7f05638f7b94e0
Source dataset
uspto-grants-1990_06
Patent number
US04931083

Reaction notes

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