反应详情

105 g of 1-benzyl-4-piperidinemethanol hydrochloride, 2 l of ethanol and 12.5 g of palladinized charcoal are introduced into a Parr bottle, and a hydrogenolysis is performed at 50° C. under a pressure of 0.4 MPa. The mixture is filtered and the filtrate evaporated off under reduced pressure. 58.7 g of solid are obtained. Melting point: 128°-130° C.

1. customis performed at 50° C. under a pressure of 0.4 MPa
2. filtrationThe mixture is filtered
3. customthe filtrate evaporated off under reduced pressure