Benzoyl isothiocyanate → HCID 15053515, compound

HRID 2107237Notes

Reaction equation

HRID 2107237 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[O:13])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1.[C:14]([N:22]=[C:23]=[S:24])(=[O:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>CN(C)C=O>[C:14]([NH:22][C:23](=[S:24])[NH:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[O:13])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1)(=[O:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 68284Benzoyl isothiocyanateHCID 4356513Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate

Product 1

HCID 15053515HCID 15053515, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The reaction described in Preparation 1 was repeated, but using 20 g of ethyl 2-aminothiazol-4-ylglyoxylate, 16.5 g of benzoyl isothiocyanate, and 100 ml of dimethylformamide, giving the title compound as a pale yellow powder.

Workup

  1. customThe reaction described in Preparation 1

Sources & evidence

ORD record
ord-b32d858b14f641ce8b2227d69c8d2834
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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