Triethylamine → HCID 15053546, compound

HRID 2107294Notes

Reaction equation

HRID 2107294 reaction equation
[NH:1]1[CH2:6][CH2:5][S:4][CH2:3][CH2:2]1.Br[C:8]1[S:9][CH:10]=[C:11]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[N:12]=1.C(N(CC)CC)C>CN(C)C=O>[N:1]1([C:8]2[S:9][CH:10]=[C:11]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[N:12]=2)[CH2:6][CH2:5][S:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 67164ThiomorpholineHCID 353965Ethyl 2-bromo-1,3-thiazole-4-carboxylate

Product 1

HCID 15053546HCID 15053546, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The reaction described in Preparation 26 was repeated, but using 1.53 g of thiomorpholine, 2.36 g of ethyl 2-bromothiazole-4-carboxylate, 2.02 g of triethylamine and 40 ml of dimethylformamide, giving the title compound as a pale yellow powder.

Workup

  1. customThe reaction described in Preparation 26

Sources & evidence

ORD record
ord-a36a83bdce654d75acfa830239688c41
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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