HCID 15053547, compound → HCID 15053564, compound

HRID 2107297Notes

Reaction equation

HRID 2107297 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:8]2[S:9][CH:10]=[C:11]([C:13](OCC)=[O:14])[N:12]=2)[CH2:4][CH2:3]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([C:8]2[S:9][CH:10]=[C:11]([CH2:13][OH:14])[N:12]=2)[CH2:6][CH2:7]1

Participants

4

Reactant 2

HCID 15053547HCID 15053547, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 15053564HCID 15053564, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The reaction described in Preparation 15 was repeated, but using 4.0 g of ethyl 2-(4-methyl-1-piperazinyl)-thiazole-4-carboxylate, 0.6 g of lithium aluminum hydride and 50 ml of tetrahydrofuran, giving the title compound as white prisms.

Workup

  1. customThe reaction described in Preparation 15

Sources & evidence

ORD record
ord-feb5f56f3a72443b9987008521f7e3d8
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

Loading…