反应详情

To a refluxing solution of diphenyl ether (200 ml) was added ethyl 2-butyryl-3-(4-methoxy-3-thienylamino)-prop-2-enoate (16 g, 0.0539 mol) portionwise. On completion of the addition refluxing was continued for a further 20 minutes. The reaction mixture was allowed to cool and then diluted with petroleum ether to give a pale yellow solid, 11.85 g, m.p. 222°-225°.

1. additionOn completion of the addition
2. temperaturerefluxing
3. temperatureto cool
4. customto give a pale yellow solid, 11.85 g, m.p. 222°-225°