HCID 23044848, compound → HCID 13755285, compound

HRID 2107876Notes

Reaction equation

HRID 2107876 reaction equation
C([O:6][C:7]1[CH:12]([C:13]([O:15][CH3:16])=[O:14])[CH:11]([CH2:17][CH2:18][CH2:19][CH2:20][C:21]([O:23][CH3:24])=[O:22])[CH2:10][C:9](=[O:25])[CH:8]=1)(=O)CCC>CN(C)C1C=CN=CC=1.ClCCl>[C:7]([C:8]1[C:9](=[O:25])[CH2:10][CH:11]([CH2:17][CH2:18][CH2:19][CH2:20][C:21]([O:23][CH3:24])=[O:22])[CH:12]([C:13]([O:15][CH3:16])=[O:14])[C:7]=1[OH:6])(=[O:6])[CH2:8][CH2:9][CH3:10]

Participants

4

Reactant 1

HCID 23044848HCID 23044848, compound

Product 1

HCID 13755285HCID 13755285, compound

Reagents, catalysts & solvents 2

HCID 142844-(Dimethylamino)pyridineCatalystHCID 6344DichloromethaneSolvent

Procedure

81 parts by weight of 3-butyryloxy-4-methoxycarbonyl-5-(4-methoxycarbonylbutyl)-cyclohex-2-en-1-one and 8 parts by weight of 4-dimethylaminopyridine were dissolved in anhydrous dichloromethane, and the solution was stirred for 48 hours at room temperature. The solution was washed with 10 wt % strength hydrochloric acid and water, and dried over sodium sulfate. The solvent was distilled off under reduced pressure to give 2-butyryl-3-hydroxy-4-methoxycarbonyl-5-(4-methoxycarbonylbutyl)-cyclohex-2-en-1-one as an oil (compound no. 4).

Workup

  1. washThe solution was washed with 10 wt % strength hydrochloric acid and water
  2. dry with materialdried over sodium sulfate
  3. distillationThe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-1a92b9a1415e48089e91832b27833ed3
Source dataset
uspto-grants-1990_06
Patent number
US04936906

Reaction notes

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