Perchloric Acid → HCID 14986287, compound

HRID 2108253Notes

Reaction equation

HRID 2108253 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([OH:14])[C:9]=1[OH:15].Cl(O)(=O)(=O)=O>C(OCC)(=O)C.C(OC(=O)C)(=O)C>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([O:14][C:10](=[O:14])[CH3:11])[C:9]=1[O:15][C:9](=[O:15])[CH3:8]

Participants

5

Reactant 2

HCID 24247Perchloric AcidHCID 149862841-(6-Bromohexyl)-2,3-dihydroxybenzene

Product 1

HCID 14986287HCID 14986287, compoundYield 191.5%

Reagents, catalysts & solvents 2

HCID 7918Acetic AnhydrideSolventHCID 8857Ethyl AcetateSolvent

Procedure

To 1.0 g (3.8 mmol) of 1-(6-bromohexyl)-2,3-dihydroxybenzene in 150 mL of ethyl acetate and 15 mL of acetic anhydride was added 0.03 mL of 70% perchloric acid. The solution was left at room temperature for 1.5 hours and then was washed with sodium bicarbonate solution. After drying, the organic layer was concentrated to give 1.3 g of 1-(6-bromohexyl)-2,3-bis(acetyloxy)benzene as an oil.

Workup

  1. washwas washed with sodium bicarbonate solution
  2. customAfter drying
  3. concentrationthe organic layer was concentrated

Sources & evidence

ORD record
ord-ce444c8c7e874ed0b7c79a1bc54687b6
Source dataset
uspto-grants-1990_06
Patent number
US04937373

Reaction notes

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