Ethyl Acetate → HCID 66643053, compound

HRID 2108639Notes

Reaction equation

HRID 2108639 reaction equation
C[C:2]1[CH:7]=[C:6]([S:8][C:9]2[CH:14]=[CH:13][C:12]([O:15]C)=[C:11]([CH:17]([CH3:19])[CH3:18])[CH:10]=2)[C:5]([CH3:20])=[CH:4][C:3]=1[O:21]C.[C:23](OCC)(=O)C>CCCCCC>[CH3:20][C:5]1[CH:4]=[C:3]([OH:21])[CH:2]=[C:7]([CH3:23])[C:6]=1[S:8][C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[C:11]([CH:17]([CH3:18])[CH3:19])[CH:10]=1

Participants

4

Reactant 2

HCID 8857Ethyl AcetateHCID 66642850HCID 66642850, compound

Product 1

HCID 66643053HCID 66643053, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

3,5-dimethyl-4-(4′-hydroxy-3′-iso-propyl-phenylsulfanyl)phenol was prepared from 2,5-dimethyl-4-(3′-iso-propyl-4′-methoxy-phenylsulfanyl)-anisole according to the procedure described in example 8, step d. 1H NMR (300 MHz, DMSO-d6): δ 9.58(bs, 1H), 9.21(bs, 1H), 6.77(m, 1H), 6.63(m, 3H), 6.46(dd, 1H, J=2.7 Hz and J=8.1 Hz), 3.09(m, 1H), 2.28(s, 6H), 1.06(d, 6H, J=7.2 Hz); TLC conditions: Uniplate silica gel, 250 microns; Mobile phase=ethyl acetate 25% in hexane; Rf=0.12

Sources & evidence

ORD record
ord-1b3972f46ece46fd9b5e7cd44ccf07ef
Source dataset
uspto-grants-2009_04
Patent number
US07514419B2

Reaction notes

Loading…