Dimethylformamide → 2,2-dimethyl-4-chloro-6-cyano-2H-1,3-benzoxazine

HRID 210918Notes

Reaction equation

HRID 210918 reaction equation
[C:6](#[N:7])[c:8]1[cH:9][cH:10][c:11]2[c:12]([cH:20]1)[C:13](=[O:19])[NH:14][C:15]([CH3:17])([CH3:18])[O:16]2.[CH3:21][N:22]([CH3:23])[CH:24]=[O:25].[P:1]([Cl:2])([Cl:3])([Cl:4])=[O:5]>>[Cl:3][C:13]1=[N:14][C:15]([CH3:17])([CH3:18])[O:16][c:11]2[cH:10][cH:9][c:8]([C:6]#[N:7])[cH:20][c:12]21

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24813Phosphorus oxychlorideHCID 108219722,2-dimethyl-6-cyano-3,4-dihydro-2H-1,3-benzoxazin-4-one

Product 1

HCID 147215882,2-dimethyl-4-chloro-6-cyano-2H-1,3-benzoxazine

Sources & evidence

ORD record
ord-2a0c630c40e3417f8c57c3f6dcec4362
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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