反应详情

D6 (750 mg, 1.28 mM) in dichloromethane (5 ml) was treated with trifluoroacetic acid (5 ml) overnight at ambient temperature. The solution was concentrated and then partitioned between dichloromethane and 2M sodium hydroxide. The dichloromethane solution was washed with brine, dried and concentrated to give the title compound as a colourless solid, (477 mg).

1. concentrationThe solution was concentrated
2. custompartitioned between dichloromethane and 2M sodium hydroxide
3. washThe dichloromethane solution was washed with brine
4. customdried
5. concentrationconcentrated