Dimethyl Sulfate → HCID 86621483, compound

HRID 2109957Notes

Reaction equation

HRID 2109957 reaction equation
[N+:1]([C:4]1[CH:18]=[CH:17][CH:16]=[CH:15][C:5]=1[O:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1)([O-:3])=[O:2].[S:19]([O:24]C)([O:22][CH3:23])(=[O:21])=[O:20]>C(OCC)(=O)C>[CH3:23][O:22][S:19]([O-:24])(=[O:21])=[O:20].[CH3:23][N+:10]1[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=1[CH2:8][CH2:7][O:6][C:5]1[CH:15]=[CH:16][CH:17]=[CH:18][C:4]=1[N+:1]([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 6497Dimethyl SulfateHCID 68857749HCID 68857749, compound

Product 1

HCID 86621483HCID 86621483, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4.88 g (20 mmol) of the compound from Step 3.1 was dissolved with agitation in 60 mL of ethyl acetate and to the solution was added 2.78 g (20 mmol) of dimethyl sulfate. A colorless precipitate formed gradually. The mixture was allowed to agitate for an additional 4 hours at room temperature after which it was filtered, and the filter cake was washed with a small amount of ethyl acetate and then dried at 40° C. under vacuum.

Workup

  1. customA colorless precipitate formed gradually
  2. filtrationwas filtered
  3. washthe filter cake was washed with a small amount of ethyl acetate
  4. customdried at 40° C. under vacuum

Sources & evidence

ORD record
ord-ecfb4fb32c31433d934c03a37cc240f7
Source dataset
uspto-grants-2009_04
Patent number
US07517367B2

Reaction notes

Loading…