反应详情

温度

140 °C

2-ethyl-4H-3,1-benzoxazin-4-one (6.5 g, 37.1 mmol) and 4-aminophenol (4.05 g, 37.1 mmol) were dissolved in dimethylformamide (18 mL) and stirred at 140° C. for 10 hours. After leaving to cool to room temperature, distilled water (94 mL) was added, and the solid precipitate was filtered off. The product was recrystallized (ethanol) and the target compound (6.52 g, 66%) was obtained as light brown crystals.

1. customAfter leaving
2. temperatureto cool to room temperature
3. distillationdistilled water (94 mL)
4. additionwas added
5. filtrationthe solid precipitate was filtered off
6. customThe product was recrystallized (ethanol)