Hydroxide → tert-butyl N-[1-[5-chloro-3-(propanoylamino)-1H-pyrrolo[2,3-b]pyridin-4-yl]piperidin-3-yl]carbamate
Reaction equation
[C:26]([CH2:27][CH3:28])(=[O:29])[Cl:30].[CH3:33][N:34]1[CH2:35][CH2:36][CH2:37][C:38]1=[O:39].[Cl:40][CH2:41][Cl:42].[Li+:32].[NH2:1][c:2]1[cH:3][nH:4][c:5]2[n:6][cH:7][c:8]([Cl:25])[c:9]([N:11]3[CH2:12][CH:13]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:14][CH2:15][CH2:16]3)[c:10]12.[OH-:31].[OH2:43].[cH:44]1[cH:45][cH:46][n:47][cH:48][cH:49]1>>[NH:1]([c:2]1[cH:3][nH:4][c:5]2[n:6][cH:7][c:8]([Cl:25])[c:9]([N:11]3[CH2:12][CH:13]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:14][CH2:15][CH2:16]3)[c:10]12)[C:26]([CH2:27][CH3:28])=[O:29]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-12132143e00d4cd9b49fd9a394794f94
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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