Potassium Carbonate → HCID 67549463, compound

HRID 2113457Notes

Reaction equation

HRID 2113457 reaction equation
F[C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH3:10][C:11]1[N:12]=[CH:13][NH:14][CH:15]=1.C(=O)([O-])[O-].[K+].[K+]>>[CH3:10][C:11]1[N:12]=[CH:13][N:14]([C:2]2[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=2[C:4]#[N:5])[CH:15]=1

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 678552-FluorobenzonitrileHCID 178418800HCID 178418800, compound

Product 1

HCID 67549463HCID 67549463, compound

Procedure

In analogy to example 5a, 2-fluoro-benzonitrile was reacted with 4-methylimidazole and potassium carbonate for 16 h at 90° C. After aqueous workup the title compound was obtained as a white solid (yield: 60%). MS: m/e=184.2 [M+H]+.

Sources & evidence

ORD record
ord-80051b26a20b48e7bcbf76197f61646f
Source dataset
uspto-grants-2008_10
Patent number
US07432256B2

Reaction notes

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