4-Bromophenacyl bromide → 1-(4-Bromophenyl)-2-morpholinoethanone

HRID 2114344Notes

Reaction equation

Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Br:11])=[CH:7][CH:6]=1)=[O:4].N1CCCC1.[NH:17]1[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>>[Br:11][C:8]1[CH:9]=[CH:10][C:5]([C:3](=[O:4])[CH2:2][N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)=[CH:6][CH:7]=1

Participants

Reactant 3

HCID 74544-Bromophenacyl bromide

HCID 8083Morpholine

HCID 31268Pyrrolidine

Product 1

HCID 4108821-(4-Bromophenyl)-2-morpholinoethanone

Procedure

The title compound was prepared according to the procedure described in example 113, replacing 2-bromo-1-(3-bromophenyl)ethanone with 2-bromo-1-(4-bromophenyl)ethanone and pyrrolidine with morpholine. MS (ES) m/e 284 [M+H]+.

Sources & evidence

ORD record: ord-3a10a7c1b8b74a07b7b832e3094031b8
Source dataset: uspto-grants-2008_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07432258B2

Reaction notes

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