p-Toluidine → 5-Isopropyl-pyridine-2-sulfonic acid p-tolylamide

HRID 2115409ノート

反応式

HRID 2115409 の反応式
BrCC(N(CC)CC)=O.[NH2:10][C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=1.[CH:18]([C:21]1[CH:22]=[CH:23][C:24]([S:27](Cl)(=[O:29])=[O:28])=[N:25][CH:26]=1)([CH3:20])[CH3:19]>>[C:14]1([CH3:17])[CH:15]=[CH:16][C:11]([NH:10][S:27]([C:24]2[CH:23]=[CH:22][C:21]([CH:18]([CH3:20])[CH3:19])=[CH:26][N:25]=2)(=[O:28])=[O:29])=[CH:12][CH:13]=1

参加物

4

反応物 3

HCID 7813p-ToluidineHCID 2255452-bromo-N,N-diethylacetamideHCID 222819185-Isopropylpyridine-2-sulfonyl chloride

生成物 1

HCID 589784195-Isopropyl-pyridine-2-sulfonic acid p-tolylamide

実験手順

prepared by reaction of 2-bromo-N,N-diethylacetamide with p-toluidine and 5-isopropyl-pyridine-2-sulfonyl chloride; in contrast to the general procedure the intermediate 5-isopropyl-pyridine-2-sulfonic acid p-tolylamide was isolated and crystallized from methanol/water 10/1

出典と根拠

ORDレコード
ord-734e169ad8884674a7914955fd8abf22
出典データセット
uspto-grants-2008_10
特許番号
US07435815B2

反応ノート

読み込み中…