Potassium Carbonate → HCID 68963161, compound

HRID 2115908Notes

Reaction equation

HRID 2115908 reaction equation
[CH2:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]2[CH2:14][CH2:13][CH2:12][CH2:11]2)[C:5]=1[OH:15])[CH:2]=[CH2:3].ClC1C=C(C=CC=1)C(OO)=[O:21].C(=O)([O-])[O-].[K+].[K+]>>[CH:10]1([C:6]2[C:5]3[O:15][CH:2]([CH2:3][OH:21])[CH2:1][C:4]=3[CH:9]=[CH:8][CH:7]=2)[CH2:14][CH2:13][CH2:12][CH2:11]1

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 70297m-Chloroperbenzoic acidHCID 14421495HCID 14421495, compound

Product 1

HCID 68963161HCID 68963161, compoundYield 54.6%

Procedure

Treatment of 2-allyl-6-cyclopentylphenol (6.97 g, 0.0344 mol) with 3-chloroperoxybenzoic acid (17.83 g, 0.1033 mol, 77%) and potassium carbonate (14.0 g, 0.1013 mol) generally according to the procedure described for Intermediate 9 afforded 4.1 g (54%) of (±)-(7-cyclopentyl-2,3-dihydro-1-benzofuran-2-yl)methanol as a yellow oil. Rf=0.58 (silica, ethyl acetate:hexanes 3:7); Anal. calcd. for C14H18O2 C, 77.03; H, 8.31. Found C, 76.5; H, 8.44.

Sources & evidence

ORD record
ord-11d7d4b546f4460c884b6624de9f787d
Source dataset
uspto-grants-2008_10
Patent number
US07435837B2

Reaction notes

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