Tetrahydrofuran → 2-(1-Azido-2-phenylethyl)-1,3-thiazole

HRID 211629Notes

Reaction equation

HRID 211629 reaction equation
[O:51]1[CH2:52][CH2:53][CH2:54][CH2:55]1.[c:15]1([P:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:29][cH:30][cH:31][cH:32][cH:33]1.[c:1]1([CH2:7][CH:8]([OH:9])[c:10]2[s:11][cH:12][cH:13][n:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1.[c:34]1([P:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)(=[O:42])[N:48]=[N+:49]=[N-:50])[cH:43][cH:44][cH:45][cH:46][cH:47]1>>[c:1]1([CH2:7][CH:8]([c:10]2[s:11][cH:12][cH:13][n:14]2)[N:48]=[N+:49]=[N-:50])[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 199401P,P-Diphenylphosphinic azideHCID 19609064(R)-2-phenyl-1-(thiazol-2-yl)ethanol

Product 1

HCID 196090662-(1-Azido-2-phenylethyl)-1,3-thiazole

Sources & evidence

ORD record
ord-69bff050238e496fb073ffe5ea8fb5d8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…