Dichloromethane → HCID 9848886, compound

HRID 2116537Notes

Reaction equation

HRID 2116537 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([O:13][C:14]2[CH:15]=[C:16]([Cl:20])[CH:17]=[N:18][CH:19]=2)=[C:6]([CH:12]=1)[C:7]([O:9][CH2:10][CH3:11])=[O:8].[Cl:21][C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:23]=1[S:29](Cl)(=[O:31])=[O:30].C(Cl)Cl>CN(C)C=O>[Cl:21][C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:23]=1[S:29]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([O:13][C:14]2[CH:15]=[C:16]([Cl:20])[CH:17]=[N:18][CH:19]=2)=[C:6]([CH:12]=1)[C:7]([O:9][CH2:10][CH3:11])=[O:8])(=[O:31])=[O:30]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 5221832,6-DichlorobenzenesulfonylchlorideHCID 9948021HCID 9948021, compound

Product 1

HCID 9848886HCID 9848886, compoundYield 14%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The title compound was prepared using the procedure described in Example 3, beginning with 0.1 g of the aniline of Example 1 and 2,6-dichlorobenzenesulfonyl chloride and using dimethylformamide as solvent in place of CH2Cl2. After workup, 0.024 g (14%) of the title sulfonamide was obtained

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-65131fee14e04c73aeb92cfcd56adf28
Source dataset
uspto-grants-2008_10
Patent number
US07439242B2

Reaction notes

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