反应详情

This compound was prepared using General Method 1 (EXAMPLE 1) from 2-amino-6-chlorobenzaldehyde (0.30 g, 1.9 mmol) and 3,4-difluorobenzylmagnesium bromide (generated from 3,4-difluorobenzyl bromide and magnesium in ether, 3.9 mmol, 2 equiv) to afford 0.28 g (57%) of (±)-1-(2-amino-6-chlorophenyl)-2-(3,4-difluorophenyl)ethanol after flash chromatography (4:1 hexanes:ethyl acetate).

1. customThis compound was prepared