Sodium Sulfite → HCID 86609640, compound

HRID 2118166Notes

Reaction equation

HRID 2118166 reaction equation
[I:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH2:5]Br.[S:10]([O-:13])([O-:12])=[O:11].[Na+:14].[Na+]>CC(C)=O.O>[I:1][C:2]1[CH:3]=[C:4]([CH2:5][S:10]([O-:13])(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1.[Na+:14]

Participants

5

Reactant 2

HCID 24437Sodium SulfiteHCID 27593613-Iodobenzyl bromide

Product 1

HCID 86609640HCID 86609640, compoundYield 118.8%

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 962WaterSolvent

Procedure

A solution of 3-iodobenzyl bromide (3 g) and sodium sulphite (1.26 g) in acetone (15 ml) and water (30 ml) was heated at 70° for 3 h. The solvent was removed under reduced pressure and the residue was triturated in ether to give the title compound (3.8 g). LCMS RT=3.66 min.

Workup

  1. customThe solvent was removed under reduced pressure
  2. customthe residue was triturated in ether

Sources & evidence

ORD record
ord-613bc3abd211404c998dd2a8f31dc4a6
Source dataset
uspto-grants-2008_10
Patent number
US07442836B2

Reaction notes

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