2,5-dichloro-N'-(pentafluorobenzoyl)benzohydrazide → HCID 21982111, compound

HRID 2118366Notes

Reaction equation

HRID 2118366 reaction equation
[Cl:1][C:2]1[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][C:3]=1[C:4]([NH:6][NH:7][C:8](=[O:20])[C:9]1[C:14]([F:15])=[C:13]([F:16])[C:12]([F:17])=[C:11]([F:18])[C:10]=1[F:19])=O>O=P(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][C:3]=1[C:4]1[O:20][C:8]([C:9]2[C:14]([F:15])=[C:13]([F:16])[C:12]([F:17])=[C:11]([F:18])[C:10]=2[F:19])=[N:7][N:6]=1

Participants

3

Reactant 1

HCID 219821292,5-dichloro-N'-(pentafluorobenzoyl)benzohydrazide

Product 1

HCID 21982111HCID 21982111, compoundYield 81%

Reagents, catalysts & solvents 1

HCID 24813Phosphorus oxychlorideSolvent

Procedure

By the general method of Part B of Example 2, the reaction of 21.0 g (0.05377 mol) 2,5-dichloro-N′-(pentafluorobenzoyl)benzohydrazide in POCl3 gave a product which was recrystallized from ethanol/water to give 16.59 g (81% yield) of 2-(2,5-dichlorophenyl)-5-(pentafluorophenyl)-1,3,4-oxadiazole (10).

Workup

  1. customgave a product which
  2. customwas recrystallized from ethanol/water

Sources & evidence

ORD record
ord-c9eac6709ceb479c844ebb4b93c58f0f
Source dataset
uspto-grants-2008_10
Patent number
US07442760B2

Reaction notes

Loading…