Isopropanol → HCID 20194014, compound

HRID 2118505Notes

Reaction equation

HRID 2118505 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][N:2]=1.[Cl:11][C:12]1[CH:19]=[CH:18][CH:17]=[CH:16][C:13]=1[CH2:14]Cl.[S:20]([O-:24])([OH:23])(=[O:22])=[O:21].C(O)(C)C>C(#N)C>[S:20]([O-:24])([OH:23])(=[O:22])=[O:21].[Cl:11][C:12]1[CH:19]=[CH:18][CH:17]=[CH:16][C:13]=1[CH2:14][N+:2]1[CH2:3][CH2:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:1]=1

Participants

6

Reactant 4

HCID 3776IsopropanolHCID 119062-Chlorobenzyl chlorideHCID 61778Sulfate, hydrogenHCID 767053,4-Dihydroisoquinoline

Product 1

HCID 20194014HCID 20194014, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The title compound is prepared analogously to Example A from 3,4-dihydroisoquinoline and 2-chlorobenzyl chloride in acetonitrile. The melting point of the hydrogensulphate is 190°-192° C. (from isopropanol).

Workup

  1. customis 190°-192° C.

Sources & evidence

ORD record
ord-7a80b222e76b4858a969b9061ca94806
Source dataset
uspto-grants-1987_07
Patent number
US04678792

Reaction notes

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