Water → HCID 20192907, compound

HRID 2118663Notes

Reaction equation

HRID 2118663 reaction equation
[C:1]1([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:2]([O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]Cl)=[CH:3][CH:4]=[CH:5][CH:6]=1.[C:21]1(=[O:31])[NH:25][C:24](=[O:26])[C:23]2=[CH:27][CH:28]=[CH:29][CH:30]=[C:22]12.[K].O>CN(C)C=O>[C:1]1([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:2]([O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][N:25]2[C:24](=[O:26])[C:23]3=[CH:27][CH:28]=[CH:29][CH:30]=[C:22]3[C:21]2=[O:31])=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 962WaterHCID 201928952-[(6-Chlorohexyl)oxy]-1,1′-biphenylHCID 24194345Phthalimide potassium salt

Product 1

HCID 20192907HCID 20192907, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 1-(2-biphenyloxy)-6-chlorohexane 8.0 g) and potassium phtalimide (5.6 g) in dimethylformamide (100) ml) was heated at reflux temperature for 3 hours. The solution was cooled and poured into water, and the product was extracted out with ethyl acetate. The extract was dried and evaporated to afford N-[6-(biphenyloxy)hexyl]phthalimide.

Workup

  1. temperatureat reflux temperature for 3 hours
  2. temperatureThe solution was cooled
  3. extractionthe product was extracted out with ethyl acetate
  4. customThe extract was dried
  5. customevaporated

Sources & evidence

ORD record
ord-39d4ad115f194e5482c6d01a12fca396
Source dataset
uspto-grants-1987_07
Patent number
US04680300

Reaction notes

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