Water → HCID 70443965, compound

HRID 2118707Notes

Reaction equation

HRID 2118707 reaction equation
[ClH:1].O[CH:3]1[O:11][C@H:10]([CH2:12][OH:13])[C@@H:8]([OH:9])[C@H:6]([OH:7])[C@H:4]1[NH2:5].O.[CH2:15]([NH2:33])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]>C(O)(C)C>[ClH:1].[CH2:15]([NH:33][CH:3]1[O:11][C@H:10]([CH2:12][OH:13])[C@@H:8]([OH:9])[C@H:6]([OH:7])[C@H:4]1[NH2:5])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]

Participants

5

Reactant 3

HCID 962WaterHCID 15793OctadecylamineHCID 2723635(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol hydrochloride

Product 1

HCID 70443965HCID 70443965, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

6.45 g of D-glucosamine hydrochloride are dissolved in 30 ml of isopropanol and 10 ml of water at 60° C., and 12.1 g of stearylamine are added. The resulting clear solution is stirred for a further 10 min and then cooled to room temperature. The product which has crystallized out is filtered off with suction and washed first with ethanol/water (5:2, v/v), then with ethanol and finally with ether. The residue is dried under high vacuum.

Workup

  1. customThe product which has crystallized out
  2. filtrationis filtered off with suction
  3. washwashed first with ethanol/water (5:2
  4. customThe residue is dried under high vacuum

Sources & evidence

ORD record
ord-50604fb713ef4668a52f07c2868692c5
Source dataset
uspto-grants-1987_07
Patent number
US04680287

Reaction notes

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